ALPROLIX is the first factor IX offering prophylaxis infusion schedules starting every 7 or 10 days with the potential to extend based on your response.

Learn about ALPROLIX from MyALPROLIX Peers™


Currently infusing with ALPROLIX every 7 days

The responsibility of being a husband and father led Brian to take greater control of his hemophilia treatment. He consulted with his doctor and is on a once-weekly schedule. The avid hiker and his family are happy he is now on a regular dosing schedule.


and her son, Trey, currently infusing with ALPROLIX every 7 days

Michelle's son, Trey, is like any other kid - he loves being outside, hanging out with his brother, and playing sports, like golf. Michelle and Trey worked with his doctor to get Trey on a once-weekly infusion schedule.


Currently infusing with ALPROLIX every 14 days

Casey has a wife, two children and helps run his family business. With his busy schedule he was happy to start on an ALPROLIX every-10-day dosing interval. He has since worked with his doctor to arrive at his current every-14-day prophy infusion schedule.

The recommended starting prophylaxis regimens are either 50 IU/kg once weekly or 100 IU/kg every 10 days. Dosing regimens can be adjusted based on individual response. Talk to your healthcare provider about what might be right for you.

Children under 12 years of age may have higher factor IX body weight-adjusted clearance, shorter half-life, and lower recovery. Higher dose per kilogram body weight or more frequent dosing may be needed in these children.

ALPROLIX, Coagulation Factor IX (Recombinant), Fc Fusion Protein, is a recombinant DNA derived, coagulation factor IX concentrate indicated in adults and children with hemophilia B for:
  • Control and prevention of bleeding episodes
  • Perioperative management
  • Routine prophylaxis to prevent or reduce the frequency of bleeding episodes
ALPROLIX is not indicated for induction of immune tolerance in patients with hemophilia B.
Important Safety Information

Do not use ALPROLIX if you are allergic to ALPROLIX or any of the other ingredients in ALPROLIX.

Tell your healthcare provider if you have or have had any medical problems, take any medicines, including prescription and non-prescription medicines, supplements, or herbal medicines, have any allergies and all your medical conditions, including if you are pregnant or planning to become pregnant, are breastfeeding, or have been told you have inhibitors (antibodies) to factor IX.

Allergic reactions may occur with ALPROLIX. Call your healthcare provider or get emergency treatment right away if you have any of the following symptoms: difficulty breathing, chest tightness, swelling of the face, rash, or hives.

Your body can also make antibodies called “inhibitors” against ALPROLIX, which may stop ALPROLIX from working properly.

ALPROLIX may increase the risk of formation of abnormal blood clots in your body, especially if you have risk factors for developing clots.

Common side effects of ALPROLIX include headache and abnormal sensation of the mouth. These are not all the possible side effects of ALPROLIX. Talk to your healthcare provider right away about any side effect that bothers you or does not go away, and if bleeding is not controlled using ALPROLIX.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit, or call 1-800-FDA-1088.

Please see full Prescribing Information.