For US residents only

Alprolix® [Coagulation Factor IX (Recombinant), Fc Fusion Protein] logo
A boy, a young man run and an older man walks forward (patient portrayal)

Trusted bleed protection* every step of the way

Sign up today for helpful information about ALPROLIX® and to connect with a Sanofi Hemophilia CoRe Manager.

A boy, a young man run and an older man walks forward (patient portrayal)

Trusted bleed protection* every step of the way

Sign up today for helpful information about ALPROLIX® and to connect with a Sanofi Hemophilia CoRe Manager.

ALPROLIX is the first extended half-life (EHL) factor IX therapy for hemophilia B with over 10 years of experience across all ages and settings.

*ALPROLIX has been proven to help patients prevent bleeding episodes using a prophylaxis regimen.

ALPROLIX keeps factor IX in the body for longer

The unique design of ALPROLIX uses Fc Fusion to help mimic natural factor IX and help keep factor IX levels in your body longer.

Find your CoRe Manager and connect today
Sanofi Hemophilia Community Relations and Education (CoRe) Managers offer education and support to people living with hemophilia and their families, including treatment options and lifestyle tips. Use our CoRe Locator to find the CoRe Manager in your area.
Find my CoRe

ALPROLIX may help make treatment less burdensome

  • Since ALPROLIX is an EHL, it lasts longer in the body so you may need fewer infusions
  • Convenient dosing schedules offer flexibility and freedom to help fit the lifestyles of adults, adolescents, and kids
  • ALPROLIX is available in a range of vial sizes that may help make single-vial infusions possible
†Based on specialty pharmacy dispensing records, specialty pharmacy distributor shipment records, third-party logistics shipment records, and internal retention estimates from May 2014 through May 2023 in the United States.
“Since starting ALPROLIX...I am grateful I have the protection from bleeds I need.”
—CJ, treating with ALPROLIX since 2014
Explore patient stories
CJ is a real patient who has been treating with ALPROLIX since 2014

Important Safety Information and Indication

Indication

ALPROLIX® [Coagulation Factor IX (Recombinant), Fc Fusion Protein] is an injectable medicine that is used to help control and prevent bleeding in people with hemophilia B. Hemophilia B is also called congenital Factor IX deficiency. Your healthcare provider may give you ALPROLIX when you have surgery.

Important Safety Information

Do not use ALPROLIX if you are allergic to ALPROLIX or any of the other ingredients in ALPROLIX.

Tell your healthcare provider if you have or have had any medical problems, take any medicines, including prescription and non-prescription medicines, supplements, or herbal medicines, have any allergies and all your medical conditions, including if you are pregnant or planning to become pregnant, are breastfeeding, or have been told you have inhibitors (antibodies) to Factor IX.

Common side effects of ALPROLIX include headache, abnormal sensation in the mouth, and pain in your side with blood in your urine, which may be a sign of clot formation in the urinary collecting system.

Allergic reactions may occur with ALPROLIX. Call your healthcare provider or get emergency treatment right away if you have any of the following symptoms: hives, chest tightness, wheezing, difficulty breathing, or swelling of the face.

Redness to the skin at the injection site may also occur.

ALPROLIX may increase the risk of formation of abnormal blood clots in your body, especially if you have risk factors for developing blood clots. Call your healthcare provider or seek emergency care if you have symptoms of a possible abnormal blood clot, which may include: chest pain, difficulty breathing, unexpected swelling of an arm or leg with or without pain or tenderness.

Your body can also make antibodies called "inhibitors" against ALPROLIX, which may stop ALPROLIX from working properly.

These are not all of the possible side effects of ALPROLIX. Talk to your healthcare provider right away about any side effect that bothers you or does not go away, or if bleeding is not controlled using ALPROLIX.
© 2024 Sanofi. All rights reserved. ALPROLIX and Sanofi are registered trademarks of Sanofi or an affiliate. All other trademarks are the property of their respective owners. MAT-US-2021803-v7.0-10/2024 Last updated: October 2024