over 1,300 patients
have been prescribed ALPROLIX*

Arrows

ALPROLIX has been on the market for over 6 years. ALPROLIX has been prescribed for over 1,300 people in the U.S.

*Data on file. Waltham, MA; Bioverativ Therapeutics Inc.

Patient stories reflect the real-life experiences of persons diagnosed with hemophilia B who have been prescribed ALPROLIX. However, individual experiences may vary. Patient stories are not necessarily representative of what another person using ALPROLIX may experience.

The recommended starting prophylaxis regimens for adults or adolescents are either 50 IU/kg once weekly, or 100 IU/kg once every 10 days. Dosing regimen can be adjusted based on individual response.

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Hemophilia B Didn't Stop Casey From Finding His Voice

HEMOPHILIA B
DIDN'T STOP

CASEY FROM
FINDING HIS VOICE

What attracted you to ALPROLIX?

I'm a father of 2 girls, and at the time I was helping run the family business, so I was looking for a hemophilia B treatment that offered bleed and joint bleed protection* I could rely on.

What dose did your doctor recommend?

After starting me on a 10-day, 100 IU/kg regimen, I worked with my doctor to make the move to 14 days between infusions.

Why is it important to tell others about ALPROLIX?

I'm committed to sharing my experiences with others. I want to be part of helping others learn about a potential treatment option for hemophilia B —especially my 2 nephews.

What's the most surprising thing you've experienced since starting on ALPROLIX?

The ability to extend and time between infusions. That really made a big impact on my schedule.

Check out his story

Note: This is a personal account of an ALPROLIX Peer. Please talk to your healthcare provider about whether ALPROLIX may be right for you. Individual results may vary.

The recommended starting prophylaxis regimens for adults and adolescents are either 50 IU/kg once weekly, or 100 IU/kg once every 10 days. Dosing regimen can be adjusted based on individual response.

*ALPROLIX has been proven to help patients prevent bleeding episodes using a prophylaxis regimen.

Hemophilia B Didn't Stop Alex From Finding His Voice

HEMOPHILIA B
DIDN'T STOP

ALEX FROM
FINDING HIS SPIRIT

How did hemophilia affect your childhood?

I treated my moderate hemophilia B on demand when I was a kid. I spent so much time in the hospital watching the world go past my window.

When did your outlook change about your hemophilia treatment options?

I had been treating my hemophilia on demand and then my wife gave birth to our second child. That's when I decided I had to stop gambling with my health and start taking my treatment seriously.

So you looked into treating with ALPROLIX?

I heard about ALPROLIX as a Factor IX replacement treatment option at a hemophilia symposium and immediately got in touch with my doctor about trying it. After working with my doctor and starting on an every-10-day dosing regimen, I was able to extend my dose and infuse beyond every 14 days.

What is your outlook for the future?

Coaching youth soccer, sharing the passion of the game with these kids, and watching my family grow makes me happy. My doctors and I are optimistic about ALPROLIX and the bleed and joint bleed protection* it offers. My spirit will always be bigger than hemophilia B. I'm being proactive with treatment and that makes me happy.

Check out his story

Note: This is a personal account of an ALPROLIX Peer. Please talk to your healthcare provider about whether ALPROLIX may be right for you. Individual results may vary.

The recommended starting prophylaxis regimens for adults and adolescents are either 50 IU/kg once weekly, or 100 IU/kg once every 10 days. Dosing regimen can be adjusted based on individual response.

*ALPROLIX has been proven to help patients prevent bleeding episodes using a prophylaxis regimen.

Hemophilia B Didn't Stop Brian From Finding His Voice

HEMOPHILIA B
DIDN'T STOP

BRIAN FROM
AIMING FOR THE TOP

You're an avid hiker. What do you like about hiking?

There's something about setting a goal for yourself and then meeting that goal, accomplishing something not a lot of people do.

Have you always been proactive about your hemophilia?

When I was a teenager I thought that skipping infusions gave me more control over my hemophilia. Of course, I was wrong. That went on for several years, until I met my wife.

And that changed your outlook?

Totally. She cared about me, so I really started taking control of my hemophilia. At an annual exam, my hematologist told me about ALPROLIX as a Factor IX replacement treatment option and its starting dosing regimen of once a week or every 10 days. I was really excited about that.

Where to next?

I'm excited to see where hiking takes me and how far I can push myself. I feel good about the protection* I get from ALPROLIX. With the help of family and friends, I feel like there's no stopping me.

Check out his story

Note: This is a personal account of an ALPROLIX Peer. Please talk to your healthcare provider about whether ALPROLIX may be right for you. Individual results may vary.

The recommended starting prophylaxis regimens for adults and adolescents are either 50 IU/kg once weekly, or 100 IU/kg once every 10 days. Dosing regimen can be adjusted based on individual response.

*ALPROLIX has been proven to help patients prevent bleeding episodes using a prophylaxis regimen.

HEMOPHILIA B
DIDN'T STOP

BRIAN FROM
AIMING FOR THE TOP

You're an avid hiker. What do you like about hiking?

There's something about setting a goal for yourself and then meeting that goal, accomplishing something not a lot of people do.

Have you always been proactive about your hemophilia?

When I was a teenager I thought that skipping infusions gave me more control over my hemophilia. Of course, I was wrong. That went on for several years, until I met my wife.

And that changed your outlook?

Totally. She cared about me, so I really started taking control of my hemophilia. At an annual exam, my hematologist told me about ALPROLIX and a starting dosage of once a week or every ten days. I was really excited about that.

Where to next?

I'm excited to see where hiking takes me and how far I can push myself. I feel good about the protection* I get from ALPROLIX. With the help of family and friends, I feel like there's no stopping me.

Watch his video

×

INDICATION: ALPROLIX® [Coagulation Factor IX (Recombinant), Fc Fusion Protein] is an injectable medicine that is used to help control and prevent bleeding in people with hemophilia B. Hemophilia B is also called congenital Factor IX deficiency. Your healthcare provider may give you ALPROLIX when you have surgery.

important safety information and indication 

IMPORTANT SAFETY INFORMATION
Do not use ALPROLIX if you are allergic to ALPROLIX or any of the other ingredients in ALPROLIX.

Tell your healthcare provider if you have or have had any medical problems, take any medicines, including prescription and non-prescription medicines, supplements, or herbal medicines, have any allergies and all your medical conditions, including if you are pregnant or planning to become pregnant, are breastfeeding, or have been told you have inhibitors (antibodies) to Factor IX.

Common side effects of ALPROLIX include headache, abnormal sensation in the mouth, and pain in your side with blood in your urine, which may be a sign of clot formation in the urinary collecting system.

Allergic reactions may occur with ALPROLIX. Call your healthcare provider or get emergency treatment right away if you have any of the following symptoms: hives, chest tightness, wheezing, difficulty breathing, or swelling of the face.

Redness to the skin at the injection site may also occur.

ALPROLIX may increase the risk of formation of abnormal blood clots in your body, especially if you have risk factors for developing blood clots. Call your healthcare provider or seek emergency care if you have symptoms of a possible abnormal blood clot, which may include: chest pain, difficulty breathing, unexpected swelling of an arm or leg with or without pain or tenderness.

Your body can also make antibodies called "inhibitors" against ALPROLIX, which may stop ALPROLIX from working properly.

These are not all of the possible side effects of ALPROLIX. Talk to your healthcare provider right away about any side effect that bothers you or does not go away, or if bleeding is not controlled using ALPROLIX.

INDICATION
ALPROLIX® [Coagulation Factor IX (Recombinant), Fc Fusion Protein] is an injectable medicine that is used to help control and prevent bleeding in people with hemophilia B. Hemophilia B is also called congenital Factor IX deficiency. Your healthcare provider may give you ALPROLIX when you have surgery.

important safety information and indication 

IMPORTANT SAFETY INFORMATION
Do not use ALPROLIX if you are allergic to ALPROLIX or any of the other ingredients in ALPROLIX.

Tell your healthcare provider if you have or have had any medical problems, take any medicines, including prescription and non-prescription medicines, supplements, or herbal medicines, have any allergies and all your medical conditions, including if you are pregnant or planning to become pregnant, are breastfeeding, or have been told you have inhibitors (antibodies) to Factor IX.

Common side effects of ALPROLIX include headache, abnormal sensation in the mouth, and pain in your side with blood in your urine, which may be a sign of clot formation in the urinary collecting system.

Allergic reactions may occur with ALPROLIX. Call your healthcare provider or get emergency treatment right away if you have any of the following symptoms: hives, chest tightness, wheezing, difficulty breathing, or swelling of the face.

Redness to the skin at the injection site may also occur.

ALPROLIX may increase the risk of formation of abnormal blood clots in your body, especially if you have risk factors for developing blood clots. Call your healthcare provider or seek emergency care if you have symptoms of a possible abnormal blood clot, which may include: chest pain, difficulty breathing, unexpected swelling of an arm or leg with or without pain or tenderness.

Your body can also make antibodies called "inhibitors" against ALPROLIX, which may stop ALPROLIX from working properly.

These are not all of the possible side effects of ALPROLIX. Talk to your healthcare provider right away about any side effect that bothers you or does not go away, or if bleeding is not controlled using ALPROLIX.

INDICATION
ALPROLIX® [Coagulation Factor IX (Recombinant), Fc Fusion Protein] is an injectable medicine that is used to help control and prevent bleeding in people with hemophilia B. Hemophilia B is also called congenital Factor IX deficiency. Your healthcare provider may give you ALPROLIX when you have surgery.

Please see full Prescribing Information

MANUFACTURED BY
Bioverativ Therapeutics Inc.
Waltham, MA 02451 USA
U.S. License #2078

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Questions?

1-855-MYALPROLIX (1-855-692-5776)

Monday-Friday, 8am-8pm, ET

© 2021 Genzyme Corporation. All rights reserved. ALPROLIX is a registered trademark of Bioverativ Therapeutics Inc., a Sanofi company.

MAT-US-2021805-V3.0-10/2021 LAST UPDATED: OCTOBER 2021

© 2021 Genzyme Corporation. All rights reserved. ALPROLIX is a registered trademark of Bioverativ Therapeutics Inc., a Sanofi company.

MAT-US-2021805-V3.0-10/2021 LAST UPDATED: OCTOBER 2021

Questions?

1-855-MYALPROLIX (1-855-692-5776)

Monday-Friday, 8am-8pm, ET